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WebED Education, Outreach and TrainingA Short Course: Using Modeling and StatisticsLines and Curves of Best Fit Lines and curves of best fit are used to make predictions based on how the data are distributed. Lines of Best Fit
These are popular statistical topics. Lines of best fit can be found by hand, calculator, or computer software. This web site provides an investigation of Lines of best fit. and access to other Web sites for more information on similar topics. Learn more about lines of best fit from this Google search by clicking here. Curves of Best Fit
There is actually a web site called www.curvefit.com. This site provides an in-depth look at curve fitting and non-linear regression. At this web site you can download a demo copy of a software package called Prism. It may be worth your while to check this out to see if you may want to use it with your students. Nonlinear regression fits a mathematical model to your data. What is a model? A mathematical model is a simple description of a physical, chemical or biological state or process. Using a model can help you think about chemical and physiological processes or mechanisms, enabling you to design better experiments and make sense of the results. "A mathematical model is neither a hypothesis nor a theory. Unlike scientific hypotheses, a model is not verifiable directly by an experiment. For all models are both true and false.... The validation of a model is not that it is "true" but that it generates good testable hypotheses relevant to important problems. " (R. Levins, Am. Scientist 54:421-31, 1966) A simple model relates two variables with a straight line. Y equals a slope times X plus an intercept. You can fit this model to your data using linear regression, to determine the best-fit values of the slope and intercept. See Linear regression. Linear regression is special, because the math is so simple and you can compute the best-fit values of slope and intercept by hand if you wanted to. Other models require more difficult calculations, but the idea is the same. When you fit a model to your data, you obtain best-fit values that you can interpret in the context of the model. For example, you can determine rate constants, equilibrium binding constants, etc. In most circumstances, you'll be able to use standard models developed by others. You will only need to develop new models if you work with new experimental systems, or need to extend conventional models to new situations.
Please contact Al-Azad Iqbal or Steve Gordon for Questions and Comments - Updated 9/5/07 |
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