Bioinformatics Software Development Projects

HIPPA Compliant Web-based Framework for the Ohio BioRepository

Principal Investigator: Bill Tacon, Omeris
Funding Source: Ohio Department of Development
Duration: December 2003 - December 2006

The Ohio BioRepository (OBR), comprising a human tissue specimen repository and associated searchable database, is led by Omeris in partnership with the Ohio Supercomputer Center (OSC), with support from Ohio State University’s Human Tissue Resource Network (HTRN). The repository provides researchers ready access to tissues stored under a variety of preservation techniques ensuring the presence of low abundance mRNAs, and a separate formalin-fixed paraffin block tissue archive. The repository will become a unique asset for fast turnaround on human research studies.

The Ohio BioRepository initiative needed a secure way of capturing annotated pathology report data. The annotated data or protected heath information (PHI) was to later be converted to non-PHI and be accessible by researchers interested in conducting research on the tissue specimens. The Ohio Supercomputer Center (OSC) had the tasks of designing the web interfaces, creating and hosting the web sites and maintaining the database for the Ohio BioRepository. The developed annotation system allows for the secure capture of PHI data, viewing the reports and searching on the data. The subsequent public site, used to search sanitized information, was built using a flexible framework that allows for a maintainable web interface. The framework allows search criteria options to be easily changed.

Collaborative Organizations: Omeris (lead), The Ohio State University Medical Center, Phylogeny and OSC-Springfield.

Update yourself on the progress of the Ohio BioRepository project with the presentation given March 7, 2006 at the OSC Windows on the Future conference. View presentation here.

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