Invention/Discovery

From Milan, Edison holds 1,093 patents, more than any other American. Three of Edison’s most famed inventions are the light bulb, the phonograph, and the kinetoscope, an early version of a film projector. Edison’s inventions forever changed the way American’s work and live.

Next-gen Sequencing

With assistance from the Ohio Supercomputer Center (OSC), Research Scientist Yue Zhao, Ph.D., leads several classroom and lab sessions for an introductory bioinformatics course taught at The Ohio State University by Lijun Cheng, Ph.D., assistant Professor of biomedical informatics.

Sentence Pair Modeling

With the increased information-age use of voice interfaces and chatbots, Natural Language Processing (NLP) is becoming one of the world’s most significant technologies, drawing from aspects of computer science, artificial intelligence and linguistics.

Gene Regulation

“The origins or causes of diseases determine how they manifest illness and what we can do about them,” explained Matthew T. Weirauch, Ph.D., an associate professor in the Center for Autoimmune Genomics and Etiology at Cincinnati Children’s Hospital and the pediatrics department at the University of Cincinnati College of Medicine.

Antibiotic Resistance

Antibiotic resistance causes 23,000 deaths and two million infections each year in the United States, according to the Centers for Disease Control and Prevention. Across the globe, antibiotic resistance is growing, and it is a threat to everything from food production to healthcare to saved lives.

Maritime Viruses

Matthew Sullivan, Ph.D., and the Ohio Supercomputer Center (OSC) have teamed up to give scientists insight into how to better study viruses found in a variety of communities. This information could prove invaluable to understanding everything from what’s going on inside our bodies to how we might combat climate change.

Big Data Challenges

Researchers and clinicians at The Ohio State University’s Wexner Medical Center rely upon the staff members of the Biomedical Informatics Shared Resource (BISR) to address their high-throughput, high-dimensional biological data-analysis needs, such as for next-generation sequencing research.

Biological Photoreceptors

In the emerging field of optogenetics, scientists are working to develop light-responsive proteins (photoreceptors) that will allow them to observe the nerve impulses in the brain or to control specific cellular features, such as metabolic pathways, gene expression and ion channels.

Biomolecular Machines

The cornerstone of an effective therapeutic drug development program is a rock-solid computational protocol that accurately and efficiently illustrates how molecules interact within the medicine and inside the human body. That information can be used to help fight and cure disease.

Processing Power

Richard Hughes, Ph.D., has an impressive resume in the world of physics: He was a leading member of the team that discovered top quark, contributed to the search for dark matter in the Milky Way halo, was an integral part of the discovery and study of the Higgs Boson at the Large Hadron Collider—oh, and has founded his own company and is also a professor of physics at The Ohio State University.

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