AlphaFold 3 Warning: NVIDIA Driver Version Mismatch

Category: 
Resolution: 
Unresolved
Affected Software: 

While running AlphaFold 3, you may encounter the following warning message:

025-08-27 12:44:10.888652: W external/xla/xla/service/gpu/nvptx_compiler.cc:930] The NVIDIA driver's CUDA version is 12.4 which is older than the PTX compiler version 12.6.77. Because the driver is older than the PTX compiler version, XLA is disabling parallel compilation, which may slow down compilation. You should update your NVIDIA driver or use the NVIDIA-provided CUDA forward compatibility packages.

This occurs because the host NVIDIA driver does not meet the minimum requirement for the CUDA version installed in the AF3 container. However, based on community discussions (reference), there should be no significant performance impact. You can continue to use AF3 at OSC without any issues.

We are planning to upgrade the NVIDIA driver in the near future. Once the upgrade is complete, this warning message will no longer appear.