Research

University of Maine scientist relies on OSC resources for data-intensive research on pathogen infections in wildlife

University of Maine scientist Pauline Kamath conducts research on the dynamics of infectious diseases that can spread among wildlife, with the use of the high performance computing (HPC) resources at the Ohio Supercomputer Center (OSC). Kamath, an associate professor of animal health, analyzes genetic, ecological, immunological and epidemiological data to study the evolution and transmission of harmful pathogens in animals to better understand how to treat and control infections.

Karyopharm Therapeutics scientists search for biomarkers to yield targeted patient treatments

A drug designed to treat a certain type of cancerous tumor might work well in some patients but not others. To determine why, scientists can study whether specific genetic mutations may impact the therapy’s effectiveness.

Karyopharm Therapeutics, a commercial-stage pharmaceutical company pioneering novel cancer therapies, is taking a closer look at these unique molecular characteristics of different cancers with the help of the Ohio Supercomputer Center (OSC).

Researchers use deep neural networks to predict transcription factor binding

Emily Miraldi, assistant professor in the Divisions of Immunobiology and Biomedical Informatics at Cincinnati Children’s Hospital, Department of Pediatrics at University of Cincinnati School of Medicine, leads an “immune-engineering” research group that uses mathematical modeling of the immune system to predict immune responses and understand disease.

Ecosystem for Research Networking develops platform for remote scientific instrument control

The Ecosystem for Research Networking (ERN), a team consisting of members from Rutgers University, MGHPCC, Omnibond, Virginia Tech, UMass Amherst, Penn State University and Pegasus, is developing a way to use scientific instruments remotely online. The project seeks to improve access to high-cost, specialized equipment to advance national research initiatives.

Researchers examine pipeline corrosion at the molecular level

When he joined the Ohio University faculty in 2015, Sumit Sharma found a new application for his expertise in molecular modeling and simulations: understanding pipeline corrosion.

The university’s Institute for Corrosion and Multiphase Technology investigates the causes of—and solutions for—this costly problem for the oil and gas industry. Although energy companies had been adding corrosion inhibitors to pipelines, the industry wanted to learn more about how the inhibitors work at the molecular level, Sharma said.

Professor builds Ohio State course around research using the Ohio Supercomputer Center

Chris Hadad has been a client of the Ohio Supercomputer Center (OSC) for over two decades and leads one of the most active accounts. A professor of organic chemistry at
The Ohio State University, Hadad is currently developing medical countermeasures against organophosphorus chemical nerve agents used in chemical warfare and as pesticides in agriculture.

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