Biological Sciences

Biological Sciences icon

Ohio’s bioscience researchers are leveraging the resources of the Ohio Supercomputer Center to gather and analyze massive amounts of genetic, molecular and environmental data to better understand human physiology, individualize diagnoses and treat diseases.

Metagenomic Data

The oldest forms of life on Earth, bacteria and archaea, have managed to evolve and adapt to Earth’s changing environment over billions of years. As a result, bacteria and archaea could hold the answers to the persistence of complex life.

Antibiotic Resistance

Keith Marsolo and his team are developing novel techniques that could be used to more quickly identify patients whose bodies no longer respond to standard-use antibiotics. Sick children at CCHMC can develop this resistance after the many rounds of different antibiotics they receive to ward off infections from their weakened immune systems. 

Cell Communication

Plexins receive guidance cues from other proteins and transmit signals through the lipid membrane, regulating cell migration and targeting processes. However, if a signal is not transmitted correctly through plexin, studies have shown that this could result in serious neurological disorders.

OSC and Our Vision

Here at the Ohio Supercomputer Center, we take great pride in providing powerful resources to help accelerate discovery.

The raw data tells part of our story: In 2013, the Ohio Supercomputer Center delivered more than 82 million CPU core-hours, for more than 3.3 million jobs. But behind these numbers lies the rest of our story: OSC exists to enable science.

PHOTOVOLTAIC CELLS

With more than 120 terawatts of solar power irradiating the earth, photovoltaics offers the promise of essentially limitless energy for powering society. The reality, though, depends on whether the cost of the technology can be made competitive with more traditional carbon-based sources.

HPV CANCER GENESIS

Human papillomavirus (HPV) causes about 610,000 cases of cancer worldwide, accounting for about 5 percent of all cancer cases and including virtually all cases of cervical cancer. Scientists have long known that certain types of HPV cause cancer, but they don’t completely understand all the steps that are involved.

JOINT BIOMECHANICS

A recent study into the biomechanics of the necks of ants – which can amazingly lift objects up to 1,000 times heavier than its body – might unlock one of nature’s little mysteries and, quite possibly, open the door to advancements in robotic engineering.

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