Biological Sciences

Biological Sciences icon

Ohio’s bioscience researchers are leveraging the resources of the Ohio Supercomputer Center to gather and analyze massive amounts of genetic, molecular and environmental data to better understand human physiology, individualize diagnoses and treat diseases.

Estrogen Receptors

A critical first step oncologists must take after finding a patient has breast cancer is to look for overexpressed hormone receptors in the cancer cells. This determines the type of therapy that will be used to most effectively combat the disease.

Botanical Alternatives

Sometimes numbers can be startling.

For instance, natural rubber is used in 50,000 commercial products, including 400 medical devices, because of its unique properties with regard to resilience, elasticity, abrasion and impact resistance, efficient heat dispersion and malleability at cold temperatures. It’s a critical raw material that developed countries simply can’t live without.

Hearing Loss

The difference between hearing and a lifetime of silence sometimes lies in the integrity of tiny inner ear proteins. Before Marcos Sotomayor, Ph.D., began studying these proteins, very little was known about hearing at the molecular level.

Bioinformatics Tools

In less than 10 years, the way genetic data has been collected has sped up in a major way. Previously, collecting data from a species was done one gene at a time, on an individual-by-individual basis, but new sequencing technologies allow researchers to process hundreds of thousands of genes at a time.

2015-16 OSC Overview

In 2016, the Ohio Supercomputer Center arrived at another crossroads. We began installation of the most powerful supercomputer in the history of the center. We swapped out almost all of our storage and other infrastructure, essentially rebuilding OSC’s production infrastructure from the ground up.

Noise Generation

The noise from jet-engine exhausts can cause substantial hearing loss for crewmen and airport personnel and activate restrictive regulations and/or fees for airlines. The large turbulent eddies within the jet plume—also known as large-scale coherent structures—produce the majority of the noise in the aft angles of the engine.

Jet Propulsion

For all the different moving parts that go into mechanical engineering systems, the gas turbine is a relatively simple design: a large rotor fitted with vanes is made to revolve by a fast-moving gas flow.

The Kondo Effect

Several years ago, a Physics World article posed the question, “Why would anyone still want to study a physical phenomenon that was discovered in the 1930s, explained in the 1960s and has been the subject of numerous reviews since the 1970s?”

Alloy Deformation

The compelling need for energy efficiency in the transportation industry provides a strong motivation for the increased use of lightweight engineering materials  such as titanium and magnesium alloys that will lead to weight reduction. 

OSC overview

Since the creation of the Ohio Supercomputer Center (OSC) in 1987, the center’s staff has provided the critical services that allow Ohio researchers, professors and students to achieve great new levels of success, from empowering amazing scientific discoveries to partnering on remarkable industrial innovations.

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