Biological Sciences

Biological Sciences icon

Ohio’s bioscience researchers are leveraging the resources of the Ohio Supercomputer Center to gather and analyze massive amounts of genetic, molecular and environmental data to better understand human physiology, individualize diagnoses and treat diseases.

Big Data

In 2017, OSC, in partnership with Scientel IT Corp, displayed the power of the Owens Cluster by running the single-largest scale calculation in its history.

Scientel IT Corp, a Big Data specialist company, used 16,800 cores of the Owens Cluster to test a new database software optimized to run on supercomputer systems. The seamless run created 1.25 Terabytes of synthetic data.

Stress Tolerance

While most of us try to distance ourselves from biting, blood-sucking creatures, Josh Benoit, Ph.D. and his research group at the University of Cincinnati spend their days getting to know them very well – down to the genes and genomics. The idea is the more we understand ticks and other blood feeding arthropods, the better we can avoid and eliminate them.

Particle Physics

Illustration from Giblin's research

Understanding particle physics gives us answers to the fundamentals of science. To better understand particle physics, Tom Giblin, Ph.D., looks to cosmology, the study of the evolution of the early universe.

Fuel Efficiency

Illustration from Selamet's Research

More than 140 years ago, when the first four-stroke cycle, internal combustion engine was invented, it became the prototype for the modern automobile powertrains. As long as those engines have existed, however, “knock” has been a limiting factor to the performance of engines.

With the help of the Ohio Supercomputer Center, Ahmet Selamet, Ph.D., is tackling that problem head on.

Novel Nanostructures

Illustration from Frajian's research

For most energy applications, heat is a byproduct of a reaction, cast off as unusable energy. But as the world moves toward energy efficiency, scientists are looking at ways to effectively channel heat possibly back into electricity, so less energy is wasted.

Energy Storage

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With the rise of energy storage applications for such things as rechargeable Lithium ion batteries and solar cells, graphene and graphene-based nanocomposites have attracted a lot of interest.

Tricuspid Valves

Illustration from Amini's research

Tricuspid valve surgery is a common heart valve procedure in the United States, but it is one with poor long-term outcomes. In fact, studies show that up to 45 percent of those who receive tricuspid valve surgery suffer a recurrence of problems, in some cases as early seven years after surgery. In one-third of the cases, a second operation is required.

Lung Microbe

For patients facing chronic lung disease, the third leading cause of death in the U.S., the ultimate end-stage treatment is a lung transplant. Unfortunately, the survival rate for lung transplant patients is lower than that of other organ transplants due to infections and tissue rejection.

Cancer Research

In the Department of Genetics at Case Western Reserve University, Thomas LaFramboise, Ph.D., and his research team are discovering which genetic mutations determine a person’s susceptibility to developing leukemia.

RNA Signaling

The rise of antibiotic resistance among common infectious bacteria is a worrisome health threat that has many scientists looking for a solution. Jennifer Hines, Ph.D., professor of chemistry and biochemistry at Ohio University, is one of the few looking to ribonucleic acid (RNA) structures for new drug discovery.

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