RELION (REgularised LIkelihood OptimisatioN) is a stand-alone computer program for the refinement of 3D reconstructions or 2D class averages in electron cryo-microscopy.
Availability and Restrictions
Versions
RELION is available on the Owens cluster. The versions currently available at OSC are:
| Version | Owens | Pitzer | Ascend | Note |
|---|---|---|---|---|
| 2.0 | X* | |||
| 3.0.4 | X | X | ||
| 3.1 | X* | X* | ||
| 3.1-gpu | X | X | Compatible with CUDA 10.2 or later | |
| 3.1.3 | X | Compatible with CUDA 10.2 or later | ||
| 4.0b | X | Compatible with CUDA 10.2 or later | ||
| 4.0.1 | X | Compatible with CUDA 11.8 or later |
You can use module spider relion2 for version 2.0 or module spider relion for version 3 to view available modules for a given machine. Feel free to contact OSC Help if you need other versions for your work.
Available third-party packages
| RELION | CTFFIND | MotionCor2 | GCTF | ResMap | Unblur & Summovie |
|---|---|---|---|---|---|
| 4.0b | 4.1.14 | 1.4.4 | 1.18 | 1.1.4 | 1.0.2 |
| 4.0.1 | 4.1.14 | 1.4.5 | 1.18 | 1.1.4 | 1.0.2 |
Access
RELION is available to all OSC users.
Publisher/Vendor/Repository and License Type
MRC Lab of Molecular Biology, Open source
Usage
Usage on Owens
Set-up
To set up the environment for RELION on the Owens cluster, use the command:
module load relion2/version
or
module load relion/version
where version is chosen from the available versions (omitting the version will load the default version).
Usage on Pitzer
Set-up
To set up the environment for RELION on the Pitzer cluster, use the command:
module load relion/version
where version is chosen from the available versions (omitting the version will load the default version).