RELION (REgularised LIkelihood OptimisatioN) is a stand-alone computer program for the refinement of 3D reconstructions or 2D class averages in electron cryo-microscopy.
Availability and Restrictions
Versions
RELION is available on the OSC clusters. The versions currently available at OSC are:
| Version | Pitzer | Ascend | Note |
|---|---|---|---|
| 4.0.1 | X | Built with CUDA 11.8 and OpenMPI | |
| 5.0.0 | X | X | Built with CUDA 11.8 and OpenMPI |
| 5.0.1 | X | Build with CUDA 12 and OpenMPI |
You can use module spider relion to view available modules for a given machine. Feel free to contact OSC Help if you need other versions for your work.
Available third-party packages
| Cluster | RELION | CTFFIND | MotionCor2* | GCTF | ResMap | Unblur & Summovie |
|---|---|---|---|---|---|---|
| Pitzer | 4.0.1/5.0 | 4.1.14 | 1.4.5* | |||
| Ascend | 5.0 | 4.1.14 | 1.4.5 |
* Starting with version 5.0.1, we have removed the built-in MotionCor2. If you need to use it with RELION, please visit https://emcore.ucsf.edu/ucsf-software to download a compatible version.
Access
RELION is available to all OSC users.
Publisher/Vendor/Repository and License Type
MRC Lab of Molecular Biology, Open source
Usage
Usage
Set-up
To set up the environment for RELION on the Pitzer cluster, use the command:
module load relion/version
where version is chosen from the available versions (omitting the version will load the default version).
