MotionCor2 uses multi-GPU acceleration to correct anisotropic cryo-electron microscopy images at the single pixel level across the whole frame, making it suitable for single particle and tomographic images. Iterative, patch-based motion detection is combined with spatial and temporal constraints and dose weighting.

Availability and Restrictions


The following versions are available on OSC clusters:

Version Pitzer
1.4.4 X*
* Current default version

You can use module spider motioncor2 to view available modules for a given machine. Feel free to contact OSC Help if you need other versions for your work.


MotionCor2 is available to academic/non-profit OSC users. Please review the vendor's webpage and the attached license agreement below before use. If you have any questions, please contact OSC Help.

Publisher/Vendor/Repository and License Type

University of California San Francisco, License Agreement attached below.




Usage on Pitzer


To configure your environment for use of motioncor2, run the following command: module load motioncor2. The default version will be loaded. To select a particular scipion version, use module load motioncor2/version. For example, use module load motioncor2/1.4.4 to load MotionCor2.1.4.4.

Further Reading

Documentation Attachment: